Peripheral Ossifying Fibroma Evolved Out of Pyogenic Granuloma

Peripheral Ossifying Fibroma Evolved Out of Pyogenic Granuloma

Cite this informative article because: Godinho G V, Silva C Good, Noronha B R, mais aussi al. () Peripheral Ossifying Fibroma Advanced Off Pyogenic Granuloma. Cureus 14(1): e20904. doi:/cureus.20904


The goal of the present blog post should be to establish the brand new health-related matter of a large peripheral ossifying fibroma you to definitely changed of good before diagnosed pyogenic escort service Provo granuloma into the an excellent 50-year-old lady. The in-patient was introduced getting remedy for good lesion across the buccal and you may palatal gingiva around the remaining upper basic molar. It absolutely was purplish-yellow during the color, everything 3 cm inside diameter, that have a delicate surface, an effective pedicled and you may bleeding legs, with eight many years of progression, and you will diagnosed as the pyogenic granuloma. Immediately following 36 months of evasion, the patient returned revealing a boost in the lesion and you can problem for the eating. Clinically the nodule are lobular in features, red in the colour and you can simple, pediculated, business into the surface, non-bleeding, throughout the 5 cm within its most readily useful extension, stretching to your maxillary tuberosity. The fresh new lesion was excised and introduced to possess histopathological test, which lead to brand new analysis away from peripheral ossifying fibroma. The individual is adopted for about eighteen months, prosthetically rehabilitated, that have high enough recovery without systematic signs and symptoms of reappearance.

The latest you’ll advancement of a good pyogenic granuloma so you can a great peripheral ossifying fibroma was present in this example, in accordance with the histopathological change you to definitely took place, to the growth of calcified point, fibrous maturation, and you may diminished vascular articles of your initial lesion shortly after three-years.


Pyogenic granuloma (PG) is the next most frequent reactive lesion of your own oral cavity, after inflammatory fibrous hyperplasia, the most common activated lesion. PG gift ideas a highly-circumscribed and you may distinctive line of lobular arrangement, having high central ships and you can really-shaped peripheral capillary aggregates. Whenever not dealt with, which lesion is experience fibrous maturation which have ossification and produce toward peripheral ossifying fibroma .

Peripheral ossifying fibroma (POF) is an ordinary mesenchymal lesion, predominant on the anterior maxillary gingiva of females within 2nd and you will 3rd age regarding lifetime. It is noticed an effective metaplastic process that involves the periodontal ligament in response to help you upheaval otherwise local irritants, such as biofilm, calculus, improperly modified prostheses, and you will unsatisfactory building work [2,3]. The brand new progression out of PG in order to POF is actually explained the help of its clinical and you will histopathological parallels; however, you should note that not all POF evolves out-of an effective PG. The fresh new mineralized role formed can vary certainly one of cementum, bones, and you will dystrophic calcification .

So it statement merchandise the case out-of a giant peripheral ossifying fibroma one to evolved away from a lesion before recognized due to the fact pyogenic granuloma into the a good fifty-year-dated lady.

Situation Demonstration

A beneficial fifty-year-dated hypertensive lady was referred to brand new Dental and Maxillofacial Surgery and Traumatology outpatient medical center of Mato Grosso Malignant tumors Healthcare, Cuiaba, Brazil, to own remedy for a great maxillary lesion, detected since PG, once the demonstrated because of the histopathological study of an incisional biopsy did previously. Brand new microscopic breakdown contains a fragment regarding mucosa protected by stratified hyperparakeratinized squamous epithelium, which have regions of acanthosis and much time projections, spongiosis, exocytosis, and ulceration. The new lamina propria try molded because of the dense conjunctive structure, that have areas of severe cellularity and expansion off endothelial tissue getting detailed, having beginning off vascular areas and you may areas of severe chronic inflammatory penetrate which have hemorrhagic section (Shape step 1).

Profile 1: Histological picture of pyogenic granuloma proving hyperparakeratinized stratified squamous epithelium, having regions of acanthosis and you will much time projections.

Lamina propria molded by the dense connective structure, listing areas of serious cellularity and expansion out of endothelial tissue, with opening away from vascular spaces and you can aspects of extreme chronic inflammatory penetrate that have hemorrhagic section (Haemotoxylin and you may Eosin, 100x).

Medically, she presented good nodule across the buccal and palatal gingiva personal left upper first molar, everything step 3 cm in diameter, having a softer skin, purplish-red color, pedicled and you will hemorrhaging base with eight several years of advancement. Regarding the recommendation, there is certainly also the prognosis away from really serious persistent periodontitis, observing, in intraoral real test, bad oral health and generalized tooth mobility.

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